| 发明名称 |
METHODS FOR MAKING RECOMBINANT PROTEINS USING APOPTOSIS INHIBITORS |
| 摘要 |
The invention provides improved methods of making and producing recombinant proteins <i>in vitro</i> cultures of host cells using apoptosis inhibitors. The use of one or more apoptosis inhibitors in the methods can reduce apoptosis in the cell cultures and markedly improve yield of the desired recombinant proteins. |
| 申请公布号 |
WO0123592(A2) |
申请公布日期 |
2001.04.05 |
| 申请号 |
WO2000US26352 |
申请日期 |
2000.09.25 |
| 申请人 |
GENENTECH, INC. |
发明人 |
VAN DE GOOR, JANA;HAMILTON, ROBERT, W.;DIXIT, VISHVA |
| 分类号 |
C12N15/09;A61K38/00;A61P43/00;C07K14/00;C12N1/21;C12N5/10;C12N15/12;C12N15/34;C12N15/57;C12N15/67;C12P21/02 |
主分类号 |
C12N15/09 |
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