摘要 |
PROBLEM TO BE SOLVED: To obtain a compound and a phamaceutically acceptable salt thereof, useful as a smooth muscle growth inhibitor, therapeutic agent of restenosis and a therapeutic agent of nephritis by strongly inhibiting phosphorylation of PDGF receptor. SOLUTION: This carbostyryl compound is represented by the general formula (1) (R1, R2, R3, R4 and R5 are each same or different group of a hydrogen atom, a halogen atom, a hydroxy group, a nitro group, an amino group, a lower alkyl group, a lower alkoxy group or the like; R6 is a hydrogen atom or a halogen atom; R7 is a hydrogen atom, a lower alkyl group or the like; and R8 is a hydrogen atom, a halogen atom, a lower alkyl group, a hydroxy group, a carbox group, an amino group or the like).
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