发明名称 |
SYSTEMS AND METHODS FOR OPENING OBSTRUCTED BIOLOGICAL CONDUITS |
摘要 |
<p>The invention provides methods to treating an obstructed biological conduit, that include administering to the conduit an agent that can degrade extracellular matrix of obstructing tissue. Particular methods include delivery of an enzyme or a mixture of several enzymes to the area or region of obstruction wherein the enzyme(s) have the capability to degrade extracellular matrix components within the obstruction thereby restoring the normal flow of transported fluid through the conduit. The invention also includes preventively dilating a section of conduit to minimize the risk of obstruction formation.</p> |
申请公布号 |
WO0121574(A1) |
申请公布日期 |
2001.03.29 |
申请号 |
WO2000US26237 |
申请日期 |
2000.09.24 |
申请人 |
JOHNS HOPKINS UNIVERSITY;FRANANO, NICHOLAS, F. |
发明人 |
FRANANO, NICHOLAS, F. |
分类号 |
A61M25/00;A61D7/00;A61K31/00;A61K31/167;A61K38/46;A61K38/48;A61K38/55;A61K45/00;A61K45/06;A61P1/16;A61P9/00;(IPC1-7):C07C69/76 |
主分类号 |
A61M25/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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