| 发明名称 |
A METHOD OF IDENTIFYING LIGANDS TO RNA POLYMERASE SIGMA 70 SUBUNIT |
| 摘要 |
<p>A method of identifying a ligand of a bacterial sigma<70> subunit which comprises contacting the sigma<70> subunit or a portion thereof comprising the anti-sigma binding region, with a test compound and a fusion protein of an anti-sigma<70> factor of bacteriophage T4, and determining whether the test compound binds competitively with the anti-sigma<70> factor to the sigma<70> subunit or portion thereof.</p> |
| 申请公布号 |
EP1086377(A1) |
申请公布日期 |
2001.03.28 |
| 申请号 |
EP19990930078 |
申请日期 |
1999.06.07 |
| 申请人 |
ASTRAZENECA AB |
发明人 |
BALGANESH, TANJORE;RAMACHANDRAN, VASANTHI;SHARMA, UMENDER |
| 分类号 |
G01N33/569;C07K14/01;C07K14/35;C12N15/09;C12Q1/48;G01N33/15;G01N33/50;G01N33/68;(IPC1-7):G01N33/569 |
主分类号 |
G01N33/569 |
| 代理机构 |
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代理人 |
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