| 摘要 |
<p>Compounds represented by general formula (I), wherein R1 represents hydrogen, alkyl, substituted alkyl, etc.; R?2 and R3¿ each represents hydrogen, alkyl, substituted alkyl, alkoxy, etc.; X represents -CH¿2?-, -O-, or -NH-; A represents a group represented by formula (II)(wherein R?7 and R8¿ each represents hydrogen, alkyl, acyl, alkoxycarbonyl, etc.; and R?9 and R10¿ each represents hydrogen, halogeno, hydroxy, phenyl, alkyl, etc.), etc.; and E represents hydrogen, etc., or pharmacologically acceptable salts thereof. These compounds have carboxypeptidase B inhibitory activity and are useful for the treatment and/or prevention of thrombotic diseases.</p> |
