METHODS FOR TREATING MUSCULAR DYSTROPHY WITH BONE MARROW CELLS

摘要

Methods for treating muscle diseases via bone marrow transplantation of eith er allogeneic cells or autologous cells engineered to express dystrophin or oth er gene products affected in muscle diseases are disclosed. Bone marrow cells a nd bone marrow SP cells (a highly purified population of hematopoietic stem cells) can be used in the methods. Muscle diseases include muscular dystrophies, such as Duchenne muscular dystrophy, Becker muscular dystrophy and limb-girdle muscular dystrophies.