PHARMACEUTICAL COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PULMONARY DISEASE

摘要

Provided is a pharmaceutical composition containing, as an active ingredient thereof, a substituted biaryl compound represented by general formula (I), wherein, R1, W, R2 and Z are as defined in the claims and description, or a pharmacologically acceptable salt thereof. The pharmaceutical composition of the present invention is useful as a therapeutic drug and/or prophylactic drug for chronic obstructive pulmonary disease due to having an excellent anti-inflammatory effect.

主权项

1. A pharmaceutical composition for treatment and/or prevention of chronic obstructive pulmonary disease, comprising a substituted biaryl compound represented by general formula (I): wherein, R1 represents a protected or unprotected carboxy group, W represents a nitrogen atom or —CH═ group, R2 represents an ethoxy group, 1-propenyl group or 1-propynyl group, and Z represents a phenyl group, 3-fluorophenyl group, pyridin-2-yl group, pyridin-3-yl group, thiophen-2-yl group or thiophen-3-yl groupor a pharmacological acceptable salt thereof.