发明名称 DOSIMETRY FOR CALIFORNIUM-252 (<252>Cf) NEUTRON-EMITTING BRACHYTHERAPY SOURCES AND ENCAPSULATION, STORAGE, AND CLINICAL DELIVERY THEREOF
摘要 The present invention discloses a methodology for the characterization and determination of mixed-field dosimetry for &lt;252&gt;Cf Applicator Tube (AT)-type medical sources, utilizing ionization chambers, GM counters, and Monte Carlo methods. Unlike the previous methodologies, the present invention discloses a specification of dose to muscle, rather than dose to water, for clinical dosimetry of &lt;252&gt;Cf medical sources. A dosimetry protocol, similar to that utilized for ICRU-45, with parameters determined specifically for &lt;252&gt;Cf brachytherapy is disclosed. Neutron isodose distributions and data necessary for clinical implementation of &lt;252&gt;Cf AT sources are also disclosed herein. Additionally, novel methods for the encapsulation, storage, and delivery/implantation of &lt;252&gt;Cf radionuclide sources are disclosed.
申请公布号 WO0112263(A2) 申请公布日期 2001.02.22
申请号 WO2000US22762 申请日期 2000.08.18
申请人 NEW ENGLAND MEDICAL CENTER HOSPITAL 发明人 RIVARD, MARK, J.
分类号 A61K41/00;A61M36/04;A61N5/10;G21F5/015;(IPC1-7):A61N5/10 主分类号 A61K41/00
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