| 发明名称 |
WATER SOLUBLE SDZ-RAD ESTERS |
| 摘要 |
The invention provides novel water soluble pegylated esters of rapamycin, having general structure (I), wherein n is an integer from about 5 to about 450, as well as pharmaceutical compositions containing these compounds and methods for their use as immunosuppressive, anti-inflammatory, antifungal, antiproliferative and antitumor agents.
|
| 申请公布号 |
WO0112633(A1) |
申请公布日期 |
2001.02.22 |
| 申请号 |
WO2000US22419 |
申请日期 |
2000.08.16 |
| 申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
ZHU, TIANMIN;SHAH, SYED, MUZAFAR;SAUNDERS, RICHARD, WILLIAM |
| 分类号 |
A61K31/436;A61K31/445;A61K47/48;A61P1/00;A61P3/10;A61P9/10;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P17/08;A61P19/02;A61P21/04;A61P27/02;A61P29/00;A61P31/10;A61P35/00;A61P35/02;A61P37/06;C07D498/18;C08G65/329;C08G65/334;(IPC1-7):C07D498/18 |
主分类号 |
A61K31/436 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
