| 摘要 |
<p>A process for the preparation of 5-[(4-chlorophenyl)-methyl]-2,2-dimethylcyclopentanone which comprises reacting methyl 1-[(4-chlorophenyl)methyl]-3-methyl-2-oxocyclo-pentanecarboxylate or ethyl 1-[(4-chlorophenyl)methyl]-3- methyl-2-oxocyclopentanecarboxylate with sodium hydride and methyl halide and subjecting the obtained methyl 1-[(4-chloro-phenyl)methyl]-3,3-dimethyl-2-oxocyclopentanecarboxylate or ethyl 1-[(4-chlorophenyl)methyl]-3,3-dimethyl-2-oxocyclo-pentanecarboxylate to hydrolysis. The process can give high-quality 5-[(4-chlorophenyl)-methyl]-2,2-dimethylcyclopentanone, an important intermediate for the production of metconazole which is a fungicide for agricultural and horticultural use, in a high yield through simple and easy operations.</p> |
