发明名称 |
A PEPTIDE INHIBITOR OF FIBRINOGEN BLOOD CLOTTING |
摘要 |
A method of inhibiting fibrin clot formation is provided. The decorin protein, peptide, or related fragments are found to bind fibrinogen in the presence of Zinc (Zn<2+>), thus preventing the formation of fibrin clots. The decorin protein, peptide, or related fragments can be utilized as an anticoagulant and in methods of preventing and/or treating diseases and disorders characterized by clot formation.
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申请公布号 |
WO0068264(A3) |
申请公布日期 |
2001.02.15 |
申请号 |
WO2000US12668 |
申请日期 |
2000.05.10 |
申请人 |
THE TEXAS A & M UNIVERSITY SYSTEM |
发明人 |
HOEOEK, MAGNUS;YANG, VIVIAN, WEI-CHUNG |
分类号 |
A61K38/00;A61K38/17;A61P7/02;C07K14/47;(IPC1-7):C07K14/47;C07K14/75;A61K35/56;A61K9/00;G01N33/50 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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