| 发明名称 |
Hybrid interferonτ/type I interferon polypeptides |
| 摘要 |
The invention provides fusion proteins comprising an N-terminal region derived from an interferon-tau (IFN-τ) polypeptide and a C-terminal region derived from another type I interferon polypeptide, such as IFN-alpha or IFN-beta. The fusion proteins exhibit reduced cytotoxicity as compared to the corresponding unmodified type I interferons.
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| 申请公布号 |
US6174996(B1) |
申请公布日期 |
2001.01.16 |
| 申请号 |
US19980045467 |
申请日期 |
1998.03.20 |
| 申请人 |
UNIVERSITY OF FLORIDA |
发明人 |
JOHNSON HOWARD MARCELLUS;PONTZER CAROL HANLON |
| 分类号 |
A61K38/00;A61K38/21;C07K14/555;C07K14/56;C07K16/24;C12N15/20;(IPC1-7):C07K14/555 |
主分类号 |
A61K38/00 |
| 代理机构 |
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