| 摘要 |
PURPOSE: A process for producing 3-isothiazolone salt mixture, thereby the 3-isothiazolone salt mixture can be more cheaply produced in a higher yield. CONSTITUTION: The process for producing 3-isothiazolone salt mixture of 2-methyl-3-isothiazolone hydrochloride of formula(I) and 5-chloro-2-methyl-3-isothiazolone hydrochloride of formula(II) comprises the step of reacting N,N'-dimethyl-3,3'-dithiodipropionamide and a mixture of 35% of hydrogen peroxide and 35% of hydrochloric acid instead of chlorine in the presence of solvent, in which 35% of hydrogen peroxide is added into N,N'-dimethyl-3,3'-dithiodipropionamide in the ratio of 4 to 8 mole: 1 mole; 35% of hydrochloric acid is added into N,N'-dimethyl-3,3'-dithiodipropionamide in the ratio of 10 to 12 mole : 1 mole; and the solvent is toluene, benzene, xylene, ethylacetate, CH2X2, CHX3, and CH2XCH2X, wherein X is halogen.
|
