Particulate solid drug carrier, providing retarded release and high bioavailability, comprising lipid-drug conjugate, e.g. tributyrin as source of cell differentiation inhibitor butyric acid

摘要

A particulate drug carrier, in the form of a solid aggregate at room temperature, consists of at least one lipid-drug conjugate (I) as particle matrix. The bonding in (I) is covalent, electrostatic interaction, dipole moments, dispersion forces, ionic interaction, hydrogen bonding and/or hydrophobic interaction.