发明名称 Human HNEAA81 receptor
摘要 HNEAA81 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are screening methods for identifying agonists and antagonists of the interaction of the HNEAA81 receptor and its ligands in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.
申请公布号 US6162899(A) 申请公布日期 2000.12.19
申请号 US19990221456 申请日期 1999.12.28
申请人 SMITHKLINE BEECHAM CORPORATION;SMITHKLINE BEECHAM PLC 发明人 SATHE, GANESH MADHUSUDAN;HALSEY, WENDY S;CHAMBERS, JON;MUIR, ALISON;SZEKERES, PHILIP
分类号 A61K38/00;C07K14/705;C12P21/04;G01N33/50;(IPC1-7):C07K1/00;C07K14/00;C07K17/00;C07H21/04 主分类号 A61K38/00
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