发明名称 NATURAL TORILIN COMPOUND AND USE OF THE SAME AS ANTICANCER DRUG SUBSTANCE
摘要 PURPOSE: A natural torilin compound useful as an anticancer drug is provided for enhancing the efficiency of the anticancer drug, inhibiting increase of endothelial or blood vessel neoplasm, preventing activity of the matrix metallo-protease and reducing the gene expression thereof. CONSTITUTION: The natural torilin compound useful as the anticancer drug having excellent anti-tumor activity and abilities for inhibiting the increase of endothelial and blood vessel neoplasm and the reaction of matrix metallo-protease and form reducing the expression of the gene thereof is defined by the formula I and is separated and purified from Torilidis Fluctus as a medical plant. The anti-tumor composition, that is, the anticancer drug comprising pharmaceutically effective amount of the natural torilin compound is particularly used to inhibit blood vessel neoplasm and infiltration of tumor cells.
申请公布号 KR100273657(B1) 申请公布日期 2000.12.15
申请号 KR19980007348 申请日期 1998.03.05
申请人 KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 发明人 LEE, JEONG JUN;KIM, HANG SEOP;LEE, JEONG HYEONG;HONG, YEONG SU;KIM, SE WEUN;KIM, GYU WON
分类号 C07C69/738;C07C69/013;(IPC1-7):C07C69/738 主分类号 C07C69/738
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