| 摘要 |
Compounds of formula (I) are disclosed which are Fab I inhibitors and are useful in the treatment bacterial infections, wherein: R1 is Ar or Het; R2 i s H, C1-6alkyl or Ar-C0-6alkyl; X is H, C1-4alkyl, OR', SR', C1-4alkylsulfonyl , C1-4alkylsulfoxyl, CN, N(R')2, CH2N(R')2, NO2, CF3, CO2R', CON(R')2, COR', NR'C(O)R', F, Cl, Br, I, or CF3S(O)r-; R' is H, C1-6alkyl or Ar-C0-6alkyl; a nd r is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.
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