发明名称 |
BACTERIOCHLORINS AND BACTERIOPURPURINS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY AND A PROCESS FOR THEIR PRODUCTION |
摘要 |
Bacteriochlorins and bacteriopurpurins useful for photodynamic therapy and methods for their manufacture are described herein. Methods for producing th e claimed compounds include contacting meso-diacrylate porphyrin precursors wi th a solvent and a base catalyst at sufficient temperature and time to yield th e desired conversion. Reduced bacteriochlorins can be produced by contacting unsaturated bacteriochlorins or bacteriopurpurins with a hydrogenation catalyst and hydrogen. These methods provide new routes for synthesizing bacteriochlorins and bacteriopurpurins from symmetrical and asymmetrical mes o- diacrylate porphyrins. |
申请公布号 |
CA2372239(A1) |
申请公布日期 |
2000.12.07 |
申请号 |
CA20002372239 |
申请日期 |
2000.05.23 |
申请人 |
MIRAVANT PHARMACEUTICALS, INC. |
发明人 |
ROBINSON, BYRON C. |
分类号 |
A61K41/00;C07D487/22;(IPC1-7):C07D487/22;C07D209/00;C07D257/00;A61K49/00;A61P35/00;A61K31/40 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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