| 发明名称 |
SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BYARYLPENTANIC ACIDS OR DERIVATIVES THEREOF, METHODS OF PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION, AND METHOD OF MEDICAL TREATMENT |
| 摘要 |
medicine. SUBSTANCE: described are new substituted 4-biarylbutyric or 5-biarylpentanic acids or derivatives thereof of general formula: (T)xA-B-D-E-G wherein (T)xA,B,D,E,G are as defined in claim 1. Said compounds are capable of inhibiting matrix metalloprotease. Also described are method of preparation of said compounds, pharmaceutical composition based thereon and method of medical treatment. EFFECT: improved properties of the title compounds. 28 cl, 3 dwg, 429 ex
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| 申请公布号 |
RU2159761(C2) |
申请公布日期 |
2000.11.27 |
| 申请号 |
RU19970110108 |
申请日期 |
1995.11.09 |
| 申请人 |
BAJER KORPOREJSHN |
发明人 |
KHAROL'D KLINTON JUDZHEN KLJUEHNDER;GJUNTER KHANS KHAJNTS KHERBERT BENTS;DEHVID ROSS BRITTELLI;UILL'JAM KHARRISON BALLOK;KERRI ZHANN KOUMZ;BRAJAN RICHARD DIKSON;STEFAN SHNAJDER;DZHILL EHLIZABET VUD;MAJKL KRISTOFER VANZANDT;DONAL'D DZHON VOLANIN;SKOTT M. VIL'GEL'M |
| 分类号 |
A61K31/19;A61K31/215;A61K31/275;A61K31/4035;A61K31/47;A61P35/00;A61P43/00;C07C17/12;C07C17/16;C07C17/20;C07C22/04;C07C25/18;C07C45/28;C07C45/46;C07C45/56;C07C45/72;C07C47/228;C07C47/277;C07C49/813;C07C55/02;C07C57/38;C07C59/48;C07C59/56;C07C59/68;C07C59/84;C07C59/88;C07C59/90;C07C59/92;C07C61/04;C07C61/06;C07C62/22;C07C62/38;C07C63/72;C07C65/24;C07C65/34;C07C69/145;C07C69/616;C07C69/63;C07C69/712;C07C69/738;C07C69/757;C07C205/34;C07C205/56;C07C229/34;C07C229/40;C07C233/54;C07C235/18;C07C235/84;C07C255/21;C07C255/57;C07C271/22;C07C271/26;C07C271/28;C07C271/58;C07C317/44;C07C323/52;C07C323/61;C07C323/62;C07C327/32;C07D207/08;C07D207/16;C07D207/40;C07D207/404;C07D209/48;C07D209/68;C07D213/00;C07D213/30;C07D213/50;C07D213/70;C07D215/36;C07D221/14;C07D257/04;C07D263/32;C07D277/30;C07D277/74;C07D295/192;C07D307/28;C07D307/32;C07D307/33;C07D307/54;C07D307/68;C07D307/93;C07D307/935;C07D311/96;C07D317/30;C07D317/60;C07D333/00;C07D333/22;C07D333/28;C07D333/34;C07D405/06;C07D409/12;C07D413/06;C07D471/04;C07D491/04;C07D498/04;C07F9/141;C07F9/40;(IPC1-7):C07C59/88 |
主分类号 |
A61K31/19 |
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