发明名称 A CENTRIPETALLY-MOTIVATED MICROFLUIDICS SYSTEM FOR PERFORMING IN VITRO HYBRIDIZATION AND AMPLIFICATION OF NUCLEIC ACIDS
摘要 <p>This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. The microsystem platforms of the invention are provided having arrays of thermal control regions, wherein fluid applied to the platform can be placed at a temperature and maintained at that temperature for a time that is dependent on the path length of the channel in the region, the cross-sectional dimension of the channel, and the rotational speed of the platform. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.</p>
申请公布号 WO2000069560(A1) 申请公布日期 2000.11.23
申请号 US2000013131 申请日期 2000.05.12
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