A therapeutic agent for ischemic diseases

摘要

An object of the present invention is to offer a therapeutic agent for ischemic diseases having little side effects and being capable of administering safely. The effective component of the therapeutic agent for ischemic diseases of the present invention is an extract from inflammatory tissue inoculated with vaccinia virus. An extract from inflammatory tissue inoculated with vaccinia virus. protects a cell against damage by suppressing abnormal depolarization of hyppocampal pyramidal neurons during hypoxia and so can delay the time falling into cell death. The characteristic action is not observed for normal pyramidal neurons, but is expressed only in the stage of pathema during hypoxia. Therefore, the substance of the present invention is useful as a drug to treat and prevent ischemic diseases such as cerebral infarction and the like and symptoms accompanying with neuropathy caused by ischemia.