| 发明名称 |
Colon or ileum-specific glucocorticosteroid derivatives |
| 摘要 |
Novel compounds which are a glucocorticosteroid (GCS) chemically bound to a sugar, having the general formula GCS1-O-Sugar1 for colon- or ileum-specific delivery of the GCS to inflamed bowel mucosa, as well as processes for their preparation, pharmaceutical preparations containing the compounds and the use of said compounds in therapy.
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| 申请公布号 |
US6140308(A) |
申请公布日期 |
2000.10.31 |
| 申请号 |
US19990261247 |
申请日期 |
1999.03.03 |
| 申请人 |
AKTIEBOLAGET ASTRA |
发明人 |
BRATTSAND, RALPH LENNART;EDMAN, PETER;HOEGBERG, THOMAS;NILSSON, STINABRITT;THALEN, BROR ARNE;ULMIUS, JAN ERIK |
| 分类号 |
A61K31/58;A61P1/00;A61P29/00;C07J;C07J71/00;(IPC1-7):A61K31/70 |
主分类号 |
A61K31/58 |
| 代理机构 |
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