| 发明名称 |
Method and compounds for the inhibition of adenylyl cyclase |
| 摘要 |
The present invention reveals a new series of derivatives and analogues of adenine and adenosine, i.e., 3'-adenosine derivatives, which inhibit adenylyl cyclase activity. These newly synthesized compounds include the most potent inhibitors of adenylyl cyclases known. The present invention also discloses a method for measuring the inhibition of adenylyl cyclase activity.
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| 申请公布号 |
US6132957(A) |
申请公布日期 |
2000.10.17 |
| 申请号 |
US19980071779 |
申请日期 |
1998.05.04 |
| 申请人 |
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK |
发明人 |
JOHNSON, ROGER A.;DESAUBRY, LAURENT;SHOSHANI, ILANA |
| 分类号 |
C07H19/16;C07H19/20;C12Q1/527;(IPC1-7):C12N9/00;C07D473/00 |
主分类号 |
C07H19/16 |
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