发明名称 |
BRAIN OR HEART CYCLIC NUCLEOTIDE GATED ION CHANNEL COMPOUNDS AND USES THEREOF |
摘要 |
The present invention provides an isolated nucleic acid encoding a BCNG protein or a portion thereof or BCNG-related protein or a portion thereof. The present invention further provides a method for identifying a nucleic acid in a sample which encodes a BCNG protein or a BCNG-related protein. The present invention also provides a method for testing whether a compound affects the expression of a BCNG protein or a BCNG-related protein. In addition, the present invention further provides a method for identifying a compound capable of interacting with a BCNG protein or a BCNG-related protein. Also, the present invention provides a method for identifying a compound capable of modulating BCNG protein or BCNG-related protein activity. Further, the present invention also provides a method of treating a condition in a subject which comprises administering to the subject an amount of the provided compound, effective to treat the condition. Finally, the present invention provides a pharmaceutical composition which comprises the provided compound and a pharmaceutically acceptable carrier. |
申请公布号 |
EP1042460(A1) |
申请公布日期 |
2000.10.11 |
申请号 |
EP19980964946 |
申请日期 |
1998.12.23 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
KANDEL, ERIC, R.;SANTORO, BINA;BARTSCH, DUSAN;SIEGELBAUM, STEPHEN;TIBBS, GARETH;GRANT, SETH |
分类号 |
G01N33/50;A61K9/08;A61K9/12;A61K9/16;A61K9/20;A61K38/00;A61K45/00;A61P9/00;A61P25/08;A61P25/16;A61P25/28;C07K14/47;C07K14/705;C07K16/18;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/02;C12N5/10;C12N15/00;C12N15/09;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):C12N15/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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