发明名称 BRAIN OR HEART CYCLIC NUCLEOTIDE GATED ION CHANNEL COMPOUNDS AND USES THEREOF
摘要 The present invention provides an isolated nucleic acid encoding a BCNG protein or a portion thereof or BCNG-related protein or a portion thereof. The present invention further provides a method for identifying a nucleic acid in a sample which encodes a BCNG protein or a BCNG-related protein. The present invention also provides a method for testing whether a compound affects the expression of a BCNG protein or a BCNG-related protein. In addition, the present invention further provides a method for identifying a compound capable of interacting with a BCNG protein or a BCNG-related protein. Also, the present invention provides a method for identifying a compound capable of modulating BCNG protein or BCNG-related protein activity. Further, the present invention also provides a method of treating a condition in a subject which comprises administering to the subject an amount of the provided compound, effective to treat the condition. Finally, the present invention provides a pharmaceutical composition which comprises the provided compound and a pharmaceutically acceptable carrier.
申请公布号 EP1042460(A1) 申请公布日期 2000.10.11
申请号 EP19980964946 申请日期 1998.12.23
申请人 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 发明人 KANDEL, ERIC, R.;SANTORO, BINA;BARTSCH, DUSAN;SIEGELBAUM, STEPHEN;TIBBS, GARETH;GRANT, SETH
分类号 G01N33/50;A61K9/08;A61K9/12;A61K9/16;A61K9/20;A61K38/00;A61K45/00;A61P9/00;A61P25/08;A61P25/16;A61P25/28;C07K14/47;C07K14/705;C07K16/18;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/02;C12N5/10;C12N15/00;C12N15/09;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):C12N15/00 主分类号 G01N33/50
代理机构 代理人
主权项
地址