发明名称 Treating bone degeneration and osteoarthritis with carprofen and its derivatives
摘要 A method of treating or preventing degeneration of articular cartilage or subchondral bone by administering a compound of formula (I), wherein R2 is -[C(X)(Y)]n-C(=O)-A; A is hydroxy, alkoxy, amino, hydroxy-amino, alkylamino, X and Y are independently hydrogen or alkyl, n is 1 or 2; R6 is halogen, alkyl, trifluoromethyl or nitro; R9 is hydrogen, alkyl, optionally substituted phenyl or phenyl-alkyl.
申请公布号 NZ335897(A) 申请公布日期 2000.09.29
申请号 NZ19990335897 申请日期 1999.05.21
申请人 PFIZER PRODUCTS INC 发明人 EVANS, NIGEL ANTHONY;KILROY, CAROLYN ROSE;LUNDY, KRISTIN MARIE;PELLETIER, JEAN-PIERRE;RICKETTS, ANTHONY PAUL
分类号 A61K9/28;A61K31/41;(IPC1-7):A61K31/41 主分类号 A61K9/28
代理机构 代理人
主权项
地址