发明名称 MAGNETIC SILICA PARTICLE FOR NUCLEIC ACID BINDING AND ISOLATION OF NUCLEIC ACID
摘要 PROBLEM TO BE SOLVED: To obtain a magnetic silica particle having excellent dispersion stability and magnetic separation, isolatable from a material containing a nucleic acid in high efficiency and with high purity, useful for nucleic acid binding in high productivity and to provide a method capable of isolating a nucleic acid from the material containing the nucleic acid in high efficiency and with high purity. SOLUTION: The magnetic silica particle contains a metal or a metal oxide composed of a multidomain and has >=0.1 m2/g and <100 m2/g specific surface area. The method for isolating a nucleic acid comprises a process for bringing the magnetic silica particle into contact with a material containing a nucleic acid in a solution for extracting the nucleic acid so as to bond the nucleic acid to the surface of the magnetic silica particle for nucleic acid binding, a process for separating the magnetic silica particle for nucleic acid binding bonded to the nucleic acid from the solution for extracting the nucleic acid by magnetism, and a process for dissociating the nucleic acid bound with the magnetic silica particle for nucleic acid binding from the magnetic silica particle for nucleic acid binding.
申请公布号 JP2000256388(A) 申请公布日期 2000.09.19
申请号 JP19990063329 申请日期 1999.03.10
申请人 JSR CORP 发明人 MASUKAWA TORU;HIKATA MIKIO;HAN KAKUN
分类号 C12N15/09;C01B33/12;C01G49/00;C07H21/02;C07H21/04;C12M1/00;(IPC1-7):C07H21/04 主分类号 C12N15/09
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