摘要 |
<p>A method of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample (102). Infrared radiation detectors measure radiation at selected analyte absorption peak, and reference wavelengths (104). Reference, and analyte signals are detected. In the presence of the selected analyte, parameter differences between reference, and analytical signals are detectable. These parameter differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample (106). Accuracy is enhanced by inducing a periodically modulated temperature gradient in the test sample. The analytical, the reference signals may be measured continuously, and the parameter difference integrated over the measurement period to determine analyte concentration.</p> |