TREATMENT OF ALPHA-GALACTOSIDASE A DEFICIENCY

摘要

The invention provides highly purified �-Gal A, and various methods for purifying it; �-Gal A preparations with altered charge and methods for making those preparations; �-Gal A preparations that have an extended circulating half-life in a mammalian host, and methods for making same; and methods and dosages for administering an �-Gal A preparation to a subject.