发明名称 Vitamin D compounds and method of preparing these compounds
摘要 The invention relates to a new vitamin D compound of the general formula wherein: R1 is a hydrogen atom or a hydroxy group; R2 is a (C1-C3)alkyl group, a hydroxy(C1-C3)alkyl group, a (C1-C2)alkoxymethyl group or a (C2-C3)alkenyl or alkynyl group; R3 is a branched or non-branched, saturated or unsaturated aliphatic 3- to 5 -membered hydrocarbon or oxahydrocarbon biradical, having at least 3 atoms in the main chain and being optionally substituted with one or more substituents selected from epoxy, fluoro and hydroxy; R4 is a sec. or tert. (C3-C6)alkyl group or a (C3-C6)cycloalkyl group; and A and B are each individually hydrogen atoms or methyl groups, or A and B form together a methylene group. The invention further relates to a method of preparing these compounds and to their use in pharmacotherapy and cosmetics.
申请公布号 USRE36854(E) 申请公布日期 2000.09.05
申请号 US19970931073 申请日期 1997.09.15
申请人 DUPHAR INTERNATIONAL RESEARCH B.V. 发明人 SESTELO, JOSE P.;MOURINO, ANTONIO;MASCARENAS, JOSE L.;HALKES, SEBASTIANUS J.;ZORGDRAGER, JAN;DIJKSTRA, GERHARDUS D. H.;VAN DE VELDE, JAN-PAUL
分类号 C07C35/32;C07C45/29;C07C49/477;C07C49/513;C07C401/00;(IPC1-7):A61K31/205;A61K31/59 主分类号 C07C35/32
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