发明名称 |
Peptide library and screening method |
摘要 |
A random peptide library constructed by transforming host cells with a collection of recombinant vectors that encode a fusion protein comprised of a carrier protein fused to a random peptide through a proteolytic cleavage site can be used to identify ligands that bind to a receptor. The screening method results in the formation of a complex comprising the fusion protein bound to a receptor through the random peptide ligand, and the random peptide can easily be identified and analyzed by virtue of the carrier protein and associated proteolytic cleavage site.
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申请公布号 |
US6107059(A) |
申请公布日期 |
2000.08.22 |
申请号 |
US19920876288 |
申请日期 |
1992.04.29 |
申请人 |
AFFYMAX TECHNOLOGIES N.V. |
发明人 |
HART, CHARLES P. |
分类号 |
C07K1/04;C07K14/395;C07K14/665;C12N15/10;C12N15/62;C12P21/04;C40B40/02;(IPC1-7):C12P21/04 |
主分类号 |
C07K1/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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