HAIR GROWTH STIMULANTS AND METHOD FOR SCREENING SUBSTANCE HAVING HAIR GROWTH STIMULATING EFFECT

摘要

Excellent hair growth stimulants having novel function mechanisms different from the conventional hair growth stimulants and a method for screening the same. The above-described hair growth stimulants contain as the active ingredient compounds exerting an effect of stimulating purine receptors (adenosine receptor, ATP receptor, etc.), an effect of potentiating the above effect, and an effect of liberating compounds having an effect of stimulating purine receptors (adenosine, adenosine derivatives, adenosine metabolites, etc.) from cells. The above-described screening method comprises adding a test substance to cells which have been transformed with an ABC transporter gene and a purine derivative receptor gene and using the calcium influx at this point as an indication.