| 摘要 |
<p>Compounds of the general formula (I): in which - one of the substituents R or R' represents an oxygen atom doubly bonded to the ring carbon and the other represents a group R1 - the symbol - - - represents a double bond conjugated to the CO group represented by one of the substituents R or R', - X represents a sulphur atom or an oxygen atom, - R1 and R2, which may be identical or different, each represent a hydrogen atom, a C1-C4alkyl group, a halogen atom, a trifluoromethyl group or a phenyl group, it being possible for R1 and R2, considered together and with the benzopyranone group to which they are linked, to form a 7,8,9,10-tetrahydrodibenzo[b,d]pyran-6-one group or a 1,2,3,4-tetrahydro-9H-xanthen-9-one group; and - Y represents a hydrogen atom or an aliphatic acyl group; a method for their preparation by reacting a compound of the formula (II) with a thioxylose derivative selected from the group consisting of the acylthioxylosyl halides, peracylated thioxyloses and acylthioxylosyl trichloro acetimidates. These compounds are useful in therapy, in particular as venous antithrombotic agents.</p> |
