METHOD FOR INDUCING DIFFERENTIATION INTO ADIPOCYTES, COMPOUNDS CONTROLLING SUCH DIFFERENTIATION AND METHOD OF SCREENING FOR SAME

摘要

It has been found out that prolactin, which is one of the components of feta l bovine serum (FBS), is capable of inducing the expression of C/EBP.beta. gen e and PPAR.gamma. gene in multipotential mesenchyme stem cells and thus differentiating these cells into adipocytes. It has been further found out that a compound regulating the differentiation into adipocytes can be screen ed by using an adipocyte differentiation system with the use of prolactin.