发明名称 Substituted (aminoiminomethyl or aminomethyl)benzoheteroaryl compounds
摘要 This invention is directed to an (aminoiminomethyl or aminomethyl)benzoheteroaryl compound of formula I which is useful for inhibiting the activity of Factor Xa by combining said compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of the formula I, methods for their preparation, their use, such as in inhibiting the formation of thrombin or for treating a patient suffering from, or subject to, a disease state associated with a physiologically detrimental excess amount of thrombin.
申请公布号 AU2207100(A) 申请公布日期 2000.07.31
申请号 AU20000022071 申请日期 1999.12.22
申请人 AVENTIS PHARMACEUTICALS PRODUCTS INC. 发明人 WILLIAM P DANKULICH;DANIEL G MCGARRY;CHRISTOPHER BURNS;TIMOTHY F. GALLAGHER;FRANCIS A. VOLZ
分类号 A61K31/4045;A61K31/4178;A61K31/433;A61K31/4355;A61K31/437;A61K31/4439;A61K31/454;A61K31/455;A61K31/496;A61K31/501;A61K31/5025;A61K31/506;A61K31/5377;A61P7/02;A61P9/10;A61P31/04;A61P31/12;A61P35/00;A61P41/00;A61P43/00;C07D209/42;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D409/12;C07D409/14;C07D413/12;C07D417/12;C07D471/04;C07D487/04;C07D491/04;C07D491/048;C07D521/00 主分类号 A61K31/4045
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