发明名称 A method for the prophylactic treatment of cataracts
摘要 The present invention is directed to a method for the prophylactic treatment of cataract. The method involves the administration of a compound of Formula Iwherein V, W and X are selected from the group consisting of hydro, hydroxyl, alkoxy, halo, an ester, an ether, a carboxylic acid group, a pharmaceutically acceptable salt of a carboxylic acid group, and -SR, in which R is hydrogen or an alkyl group, Y is selected from the group consisting of oxygen, sulfur, C(OH), and C=O, and Z is selected from the group consisting of hydro and C(O)OR1, wherein R1 is an alkyl, or an analogue or prodrug thereof or a pharmaceutically acceptable salt of any of the foregoing to an animal, such as a mammal, in particular a human, in an amount sufficient to treat cataracts prophylactically. The compound of Formula I is preferably genistein.
申请公布号 AU2207400(A) 申请公布日期 2000.07.12
申请号 AU20000022074 申请日期 1999.12.22
申请人 JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE 发明人 EUGENE DE JUAN JR.
分类号 A61K31/35;A61K31/352;A61K31/52;A61K45/06 主分类号 A61K31/35
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