| 摘要 |
<p>Drugs effective in the prevention and treatment of diseases due to abnormal production of interleukin-6, which are interleukin-6 production inhibitors containing as the active ingredient methanebis-phosphonic acid derivatives and exhibit an inhibitory effect against the production of interleukin-6. These drugs can be expected to be effective in the prevention and treatment of diseases in which interleukin-6 participates, for example, thrombocytosis, inflammatory diseases, immune response disorders, osteoporosis, rheumatoid arthritis, hypercalcemia, multiple myeloma, cachexia and nephritis.</p> |
