This invention relates to a family of bacterial polypeptides which are considered essential for gowth of both gram negative and gram positive bacteria. The family has been identified by a number of methods including computer based algorithms. The use of such polypeptides and the genes which encode them as tools for identifying novel broad spectrum antibiotics is described.
申请公布号
WO9954462(A3)
申请公布日期
2000.06.22
申请号
WO1999EP02638
申请日期
1999.04.20
申请人
GLAXO GROUP LIMITED;ARIGONI, FABRIZIO;EDGERTON, MICHAEL, DAVID;LOFERER, HANNES;PEITSCH, MANUEL, C.
发明人
ARIGONI, FABRIZIO;EDGERTON, MICHAEL, DAVID;LOFERER, HANNES;PEITSCH, MANUEL, C.