发明名称 Cell-culture reactor having a porous organic polymer membrane
摘要 A method for making a biocompatible polymer article using a uniform atomic oxygen treatment is disclosed. The substrate may be subsequently optionally grated with a compatibilizing compound. Compatibilizing compounds may include proteins, phosphorylcholine groups, platelet adhesion preventing polymers, albumin adhesion promoters, and the like. The compatibilized substrate may also have a living cell layer adhered thereto. The atomic oxygen is preferably produced by a flowing afterglow microwave discharge, wherein the substrate resides in a sidearm out of the plasma. Also, methods for culturing cells for various purposes using the various membranes are disclosed as well. Also disclosed are porous organic polymers having a distributed pore chemistry (DPC) comprising hydrophilic and hydrophobic regions, and a method for making the DPC by exposing the polymer to atomic oxygen wherein the rate of hydrophilization is greater than the rate of mass loss.
申请公布号 US6074871(A) 申请公布日期 2000.06.13
申请号 US19970903278 申请日期 1997.07.09
申请人 THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 发明人 KOONTZ, STEVEN L.
分类号 A61L27/28;A61L33/00;B01D15/08;B01D39/16;B01D67/00;B01J20/08;B01J20/10;B01J20/28;B01J20/32;B01J37/14;B29C59/14;C08J9/36;C12M1/24;C12M3/04;C12M3/06;C12N5/00;C12P21/00;G01N30/52;G01N33/543;G01N33/545;(IPC1-7):C12M3/06 主分类号 A61L27/28
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