发明名称 ANTIBODY VARIANTS WITH HIGHER BINDING AFFINITY COMPARED TO PARENT ANTIBODIES
摘要 <p>Antibody variants of parent antibodies are disclosed which have one or more amino acids inserted in a hypervariable region of the parent antibody and a binding affinity for a target antigen which is at least about two fold stronger than the binding affinity of the parent antibody for the antigen.</p>
申请公布号 WO2000029584(A1) 申请公布日期 2000.05.25
申请号 US1999027153 申请日期 1999.11.16
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