| 摘要 |
New cross-linked hyaluronic acids obtainable by reaction of activated carboxylic groups of native linear hyaluronic acid, of extractive or biosynthetic source, with a polyamine, particularly a linear alkyl diamine. The cross-linked hyaluronic acids of the invention can optionally be sulphated or hemisuccinylated and are useful as substitutes of synovial fluid, vitreous humor, as controlled-release matrices forms medicaments, as healing and antiadhesive agents, and for the preparation of vascular prosthesis, biohybrid organs, healing devices, ophthalmic and otological compositions, prosthesis, implants and medical devices.
|
