A CHROMATOGRAPHY METHOD AND A COLUMN MATERIAL USEFUL IN SAIDMETHOD

摘要

The present invention relates to a novel sorbent suitable for use as a stationary phase in a chromatography column, the core of which consists of a n organic polymer of synthetic or natural origin. Further, the carrier accordi ng to the invention exhibits a plurality of covalently bonded non-aromatic zwitterionic groups on its surface. Additionally, the invention also relates to a method for purifying a particular biological macromolecule, such as a protein or a nucleic acid, by zwitterionic ion exchange chromatography as we ll as an ion exchange column suitable for use in zwitterionic ion exchange chromatography.