| 发明名称 |
VIRUS VECTORS AND METHODS OF MAKING AND ADMINISTERING THE SAME |
| 摘要 |
The present invention provides genetically-engineered parvovirus capsids and viruses designed to introduce a heterologous gene into a target cell. The parvoviruses of the invention provide a repertoire of vectors with altered antigenic properties, packaging capabilities, and/or cellular tropisms as compared with current AAV vectors.
|
| 申请公布号 |
CA2348382(A1) |
申请公布日期 |
2000.05.18 |
| 申请号 |
CA19992348382 |
申请日期 |
1999.11.10 |
| 申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
SAMULSKI, RICHARD JUDE;RABINOWITZ, JOSEPH E.;XIAO, WEIDONG |
| 分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K39/00;A61K48/00;A61P3/00;A61P3/10;A61P7/00;A61P11/00;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P31/18;A61P35/00;C07K14/015;C07K19/00;C12N1/11;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/00;C12N7/01;C12N15/864;(IPC1-7):C12N7/01;C12N15/86;C12N15/62;C12N15/35;C12N7/02;C12N15/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
