| 发明名称 |
N-LINKED UREAS AND CARBAMATES OF HETEROCYCLIC THIOESTERS |
| 摘要 |
This invention relates to neurotrophic low molecular weight, small molecule N-linked ureas and carbamates of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity. |
| 申请公布号 |
SK57899(A3) |
申请公布日期 |
2000.05.16 |
| 申请号 |
SK19990000578 |
申请日期 |
1997.12.23 |
| 申请人 |
GUILFORD PHARMACEUTICALS INC. |
发明人 |
HAMILTON GREGORY S.;LI JIA-HE;HUANG WEI |
| 分类号 |
A61K31/40;A61K31/4439;A61P25/00;A61P25/16;A61P25/28;A61P43/00;C07D207/08;C07D207/12;C07D207/16;C07D211/60;C07D401/12;(IPC1-7):A61K31/40 |
主分类号 |
A61K31/40 |
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