发明名称 |
Dna-templated combinatorial library chemistry |
摘要 |
The present invention describes templated combinatorial chemical libraries comprised of a plurality of bifunctional molecules having both a chemical compound and a nucleic acid tag that defines the structure of the chemical compound and directs its synthesis. Also described are methods for producing, enriching and in vitro evolution of the bifunctional molecules of such libraries based on the nucleic acid tags and methods for selecting for library compounds having a desired activity. |
申请公布号 |
AU1318400(A) |
申请公布日期 |
2000.05.08 |
申请号 |
AU20000013184 |
申请日期 |
1999.10.19 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANDFORD JUNIOR UNIVERSITY |
发明人 |
PEHR B. HARBURY;DAVID R. HALPIN |
分类号 |
C07B61/00;C07H21/00;C12N15/10 |
主分类号 |
C07B61/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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