发明名称 PRODUCTION INTERMEDIATE OF ANTIBIOTIC MI43-37F11
摘要 PROBLEM TO BE SOLVED: To provide a production intermediate usable for a method of chemically producing anticancer antibiotic MI43-37F11. SOLUTION: This production intermediate of antibiotic MI43-37F11 is a compound represented by the formula (wherein, R1 and R2 are each independently hydrogen atom or a lower alkyl group; and L2 is a halogen atom). The antibiotic MI43-37F11 is produced by reacting the compound, or the product obtained after alkylating the compound, with a compound of the general formula, R3 COOX (R3 is hydrogen atom or a lower alkyl group; and X is hydrogen atom, an alkali metal or an organic base), and hydrolyzing the product.
申请公布号 JP2000119268(A) 申请公布日期 2000.04.25
申请号 JP19990312162 申请日期 1999.11.02
申请人 MERCIAN CORP 发明人 YOSHIOKA TAKEO;MIYATA RYOICHI;TONE HIROSHI;OKAMOTO ROKURO;KUMAGAI HIROYUKI;ISHIZUKA MASAAKI;TAKEUCHI TOMIO
分类号 C07D311/76;A61K31/365;A61K31/366;A61P35/00;(IPC1-7):C07D311/76 主分类号 C07D311/76
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