发明名称 |
ISOLATED MULTIMERIC COMPLEXES USEFUL IN ANALYSIS OF T CELLS, PEPTIDES USEFUL IN MAKING THE COMPLEXES, AND USES THEREOF |
摘要 |
The invention involves multicomponent complexes, which use useful in analysis of T cells. The complexes contain at least first and second binding partners, which bind to each other. The second binding partner engages a plurality of immune complexes, which comprise an NHC molecule, a beta 2 microglobulin molecule, and a peptide. Preferably, there are at least four of these immune complexes per multicomponent complex. These can be used to determine or to isolate cytolytic T cells. |
申请公布号 |
WO9950637(A3) |
申请公布日期 |
2000.04.13 |
申请号 |
WO1999US06615 |
申请日期 |
1999.03.25 |
申请人 |
LUDWIG INSTITUTE FOR CANCER RESEARCH;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD |
发明人 |
ROMERO, PEDRO;DUNBAR, ROD;VALMORI, DANILA;PITTET, MIKAEL;SPEISER, DANIEL;CERUNDOLO, VINCENZO;OGG, GRAHAM;CERROTINI, JEAN-CHARLES |
分类号 |
C07K14/74;C07K16/28;G01N33/569 |
主分类号 |
C07K14/74 |
代理机构 |
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主权项 |
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地址 |
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