发明名称 ISOLATED MULTIMERIC COMPLEXES USEFUL IN ANALYSIS OF T CELLS, PEPTIDES USEFUL IN MAKING THE COMPLEXES, AND USES THEREOF
摘要 The invention involves multicomponent complexes, which use useful in analysis of T cells. The complexes contain at least first and second binding partners, which bind to each other. The second binding partner engages a plurality of immune complexes, which comprise an NHC molecule, a beta 2 microglobulin molecule, and a peptide. Preferably, there are at least four of these immune complexes per multicomponent complex. These can be used to determine or to isolate cytolytic T cells.
申请公布号 WO9950637(A3) 申请公布日期 2000.04.13
申请号 WO1999US06615 申请日期 1999.03.25
申请人 LUDWIG INSTITUTE FOR CANCER RESEARCH;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD 发明人 ROMERO, PEDRO;DUNBAR, ROD;VALMORI, DANILA;PITTET, MIKAEL;SPEISER, DANIEL;CERUNDOLO, VINCENZO;OGG, GRAHAM;CERROTINI, JEAN-CHARLES
分类号 C07K14/74;C07K16/28;G01N33/569 主分类号 C07K14/74
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