发明名称 |
Hydroxyflavone derivatives as tau protein kinase 1 inhibitors |
摘要 |
A medicament for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity or a neurodegenerative disease which comprises as an active ingredient a substance selected from the group consisting of a hydroxyflavone derivative represented by formula (I) and a salt thereof, and a solvate thereof and a hydrate thereof, wherein R<1> represents hydrogen atom or hydroxyl group; R<2> represents hydrogen atom or a C1-C18 alkyl group which may have one or more C6-C14 aryl groups; and Ar represents a C6-C14 aryl group which may be substituted or an aromatic heterocyclic group which may be substituted. |
申请公布号 |
AU5759899(A) |
申请公布日期 |
2000.04.10 |
申请号 |
AU19990057598 |
申请日期 |
1999.09.24 |
申请人 |
MITSUBISHI CHEMICAL CORPORATION |
发明人 |
AYA SHODA;KAZUTOSHI WATANABE;KEIICHI ARITOMO;TETSUO JIKIHARA;RYOICHI ANDO;KENICHI SAITO;TOSHIYUKI HONDA;RIE KAWAMOTO |
分类号 |
A61K31/352;A61K31/381;A61K31/401;A61K31/4025;A61K31/4035;A61K31/41;A61K31/4155;A61K31/4178;A61K31/422;A61K31/443;A61K31/4433;A61K31/453;A61K31/496;A61K31/501;A61K31/506;A61K31/5375;A61P7/02;A61P9/00;A61P25/16;A61P25/28;A61P43/00;C07D311/30;C07D405/04;C07D405/12;C07D407/04;C07D409/04;C07D413/04;C07D417/04 |
主分类号 |
A61K31/352 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|