发明名称 |
Tricycle substituted with azaheterocyclic carboxylic acids |
摘要 |
The present invention relates to novel N-substituted azaheterocyclic compounds of the general formula wherein X, Y, Z, R1, R2 and r are as defined in the detailed part of the present description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation as well as their use for treatment of indications caused by or related to the secretion and circulation of insulin antagonizing peptides, e.g. non-insulin-dependent diabetes mellitus (NIDDM) and ageing-associated obesity.
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申请公布号 |
US6040318(A) |
申请公布日期 |
2000.03.21 |
申请号 |
US19980098579 |
申请日期 |
1998.06.17 |
申请人 |
NOVO NORDISK A/S |
发明人 |
ANDERSEN, KNUD ERIK;JOERGENSEN, TINE KROGH;HOHLWEG, ROLF;FISCHER, ERIK;OLSEN, UFFE BANG;POLIVKA, ZDENEK;SINDELAR, KAREL;VALENTA, VLADIMIR |
分类号 |
C07D211/34;C07D401/06;C07D405/06;C07D409/06;(IPC1-7):A01N43/40;A01N43/36;C07D211/06 |
主分类号 |
C07D211/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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