发明名称 |
Antimicrobial cationic peptides |
摘要 |
A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include NH2-KWKSFIKKLTTAVKKVLTTGLPALIS-COOH(SEQ ID NO:1)and NH2-KWKSFIKKLTSAAKKVVTTAKPLISS-COOH.(SEQ ID NO:2)Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. The peptides are particularly useful for inhibiting endotoxemia in a subject.
|
申请公布号 |
US6040435(A) |
申请公布日期 |
2000.03.21 |
申请号 |
US19960658857 |
申请日期 |
1996.05.31 |
申请人 |
UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
HANCOCK, ROBERT E. W.;KARUNARATNE, NEDRA |
分类号 |
C12N15/09;A01N37/20;A61K31/43;A61K31/545;A61K31/65;A61K31/70;A61K38/00;A61K38/16;A61P31/04;A61P31/10;A61P39/02;C07K7/08;C07K14/00;C07K14/435;(IPC1-7):C07H21/04 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|