| 摘要 |
An affinity filter and method of using same, effective in capturing and thereby removing particles characterized by surface exposure of anionic phospholipids present in a biological fluid, particularly blood or blood-derived products. Examples of other biological fluids include semen, cerebrospinal fluid, urine and mucous. The affinity filter includes a body formed with an inlet and an outlet, including a solid support and an anionic-phospholipid binding compound linked to the solid support. The positively charged anionic-phospholipid binding compound serves for specifically binding the particles characterized by surface exposure of anionic phospholipids and thereby removing the particles from the biological fluid, and particularly from blood or blood-derived products, for example in order to prepare the blood or blood-derived product for transfusion into a subject. |
